Hugo Guillamón reached 100 official matches with the Valencia CF first team in the game against Atletico Madrid. 

After his time at the VCF Academy and appearances with VCF Mestalla, Guillamón made his debut for the first team in February 2020, at just 20 years old, in a La Liga match against Real Sociedad at the Reale Arena. 

His first official game at Mestalla was in June 2020, in a derby against Levante UD.

Since then, Guillamón has established himself in the first team and was a finalist in the 2022 Copa del Rey. He has also broken into the Spain national team, participating in the 2022 World Cup in Qatar.